BIOLOGICAL-ACTIVITY OF AMINOPHOSPHONIC ACIDS

被引:1053
作者
KAFARSKI, P
LEJCZAK, B
机构
[1] Institute of Organic and Physical Chemistry, Technical University of Wroclaw
关键词
ANTIBACTERIALS; ENZYME INHIBITORS; HERBICIDES; NEUROACTIVITY; PHOSPHONATE; PHOSPHONO PEPTIDES;
D O I
10.1080/10426509108029443
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Aminophosphonates are analogues of amino acids in which a carboxylic moiety is replaced by phosphonic acid or related groups. Acting as antagonists of amino acids, they inhibit enzymes involved in amino acid metabolism and thus affect the physiological activity of the cell. These effects may be exerted as antibacterial, plant growth regulatory or neuromodulatory. Chosen representative examples of biologically active aminophosphonates are presented in some detail. © 1991, Taylor & Francis Group, LLC. All rights reserved.
引用
收藏
页码:193 / 215
页数:23
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