EUROPEAN BROWN HARE SYNDROME IN THE UK - A CALICIVIRUS RELATED TO BUT DISTINCT FROM THAT OF VIRAL HEMORRHAGIC-DISEASE IN RABBITS

The virus recovered from cases of European brown hare syndrome in the U.K. contains one major capsid protein of approximately 60 k molecular weight and morphologically resembles known caliciviruses. It has been compared with a European isolate of rabbit haemorrhagic disease calicivirus and, although it shows some antigenic similarity, it is not identical. In transmission and protection studies the virus from U.K. hares failed to produce disease in rabbits and did not effectively protect against subsequent challenge with the rabbit calicivirus.