RECENT ADVANCES AND PROSPECTIVE RESEARCHES ON MOLECULAR EPIDEMIOLOGY OF DENGUE VIRUSES

被引:3
作者
DEUBEL, V
机构
[1] Laboratory of Arboviruses, Institut Pasteur, Paris
来源
MEMORIAS DO INSTITUTO OSWALDO CRUZ | 1992年 / 87卷
关键词
DENGUE VIRUS; MOLECULAR EPIDEMIOLOGY; SEQUENCING; ENVELOPE PROTEIN;
D O I
10.1590/S0074-02761992000900021
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
The determination of amino acid changes in the envelope protein by direct sequencing of either genomic RNA or PCR-amplified cDNA fragments provides useful informations for assessing the genetic variability and the geographic distribution of the actually most widespread dengue-2 serotype. The possible link of variations in the envelope protein-gene and virus virulence is discussed.
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页码:133 / 136
页数:4
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