LOW-ANGLE LASER-LIGHT SCATTERING AND PHOTON-CORRELATION SPECTROSCOPY IN SURFACTANT VESICLES

Using low angle laser light scattering, weight averaged molecular weights, M̄w, diffusion coefficients, and hydrodynamic radii, RH, have been determined for completely synthetic surfactant vesicles, prepared by ultrasonic irradiation of dioctadecyldimethylammonium chloride. DODAC, and dihexadecylphosphate. DHP dispersion. Both the M̄w and RH values were found to decrease exponentially as a function of sonication time. At the limit, M̄w and RH for DODAC vesicles are 12.6 × 106 dalton and 396 Å, and those for DHP vesicles are 23 × 106 dalton and 595 Å. Calculations indicate both vesicles to be prolates. © 1979.