SYNTHESIS OF 9-HYDROXYPURINES - INTERMEDIATES TO NOVEL ANTIVIRAL ACYCLONUCLEOSIDES

被引：13

作者：

HARNDEN, MR ^{[1
]}

WYATT, PG ^{[1
]}

机构：

[1] SMITHKLINE BEECHAM PHARMACEUT,BIOSCI RES CTR,EPSOM KT18 5XQ,SURREY,ENGLAND

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 15期

关键词：

D O I：

10.1016/0040-4039(90)80104-T

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Synthetic approaches to 2-[(bis-t-butoxycarbonyl)amino]-9-hydroxy-6-methoxypurine (7) and 9-hydroxy-6-phthalimidopurine (15) are described. These 9-hydroxypurines are useful intermediates in the synthesis of 9-alkoxyguanine and 9-alkoxyadenine derivatives as potential antiviral agents. © 1990.

引用

页码：2185 / 2188

页数：4

共 7 条

[1] SYNTHESIS OF 9-(3-HYDROXYPROPOXY)GUANINE, A NOVEL ANTIVIRAL ACYCLONUCLEOSIDE
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[7] DIASTEREOTOPIC SELECTIVITY AT PROCHIRAL CARBON CENTERS - FUNCTIONALIZATION OF DIFFERENTIATED HYDROXYMETHYL GROUPS PROVIDES ACCESS TO EITHER STEREOISOMERIC CONFIGURATION
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