ORTHO EFFECT ON THE NITROSATION OF THE 2,3-DIPHENYL-5(2-METHOXYPHENYL)PYRROLE

被引：4

作者：

CERAULO, L

AGOZZINO, P

FERRUGIA, M

SPRIO, V

机构：

[1] Dipartimento di Chimica e Tecnologie Farmaceutiche, Palermo, 90123, Via Archirafi

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1990年 / 27卷 / 02期

关键词：

D O I：

10.1002/jhet.5570270226

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A comparison of the behaviour on the nitrosation of the isomers 5‐(2‐methoxyphenyl)‐ (1a) 5‐(3‐methoxyphenyl)‐ (1b) and 5‐(4‐methoxyphenyl)2,3‐diphenylpyrroles (1c) carried out in the usual way with iso‐amyl nitrite in a solution of sodium ethoxide in ethanol evidences that 1a is dramatically less reactive with respect to 1b and 1c. The different reactivity was ascribed to the occurrence of a strong hydrogen bond involving pyrrole NH and the ortho‐methoxy group. Copyright © 1990 Journal of Heterocyclic Chemistry

引用

页码：255 / 257

页数：3