SYSTEMIC LUPUS-ERYTHEMATOSUS AND PREGNANCY AT THE ROYAL WOMENS HOSPITAL, BRISBANE 1979-1989

被引：7

作者：

NICKLIN, JL

机构：

[1] Royal Women's Hospital, Brisbane

来源：

AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY | 1991年 / 31卷 / 02期

关键词：

D O I：

10.1111/j.1479-828X.1991.tb01800.x

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The management and obstetric outcome of 17 patients with systemic lupus erythematosus (SLE) complicating 42 pregnancies is presented. Similar to world figures there was a 14.3% incidence of therapeutic abortion, a 4.8% incidence of ectopic pregnancy, a 16.7% incidence of spontaneous abortion, a 23.8% incidence of prematurity, a 4.8% incidence of fetal death in utero (FDIU) and a 9.5% incidence of intrauterine growth retardation (IUGR). In patients with antiphospholipid antibodies the obstetric outcome was significantly worse. Pregnancies complicated by preexisting renal compromise all concluded with an adverse outcome to the conceptus. In light of the experiences at the Royal Women's Hospital and a review of the world literature, the need for a standardized approach to SLE in pregnancy and more importantly the need for a large, prospective randomized trial of low dose aspirin in these pregnancies is highlighted.

引用

页码：128 / 133

页数：6

共 39 条

[1]

Gatenby PA, Systemic lupus erythematosus and pregnancy, Aust NZ J Med, 19, pp. 261-278, (1989)

[2]

Ramsey-Goldman R., Pregnancy in systemic lupus erythematosus, Rheum Dis Clin North Am, 14, pp. 169-185, (1988)

[3]

Mor-Yosef S., Navot D., Rabinowitz R., Schenker JG, Collagen diseases in pregnancy, Obstetrical & Gynecological Survey, 39, pp. 67-84, (1984)

[4]

Tan EM, Cohen AS, Fries JF, Et al., The 1982 revised criteria for the classification of systemic lupus erythematosus, Arthritis Rheum, 25, pp. 1271-1277, (1982)

[5]

Fraga A., Mintz G., Orozco J., Orozco JH, Sterility and fertility rates, fetal wastage and maternal morbidity in systemic lupus erythematosus, J Rheumatol, 1, pp. 293-298, (1974)

[6]

Out HJ, Derksen RH, Christiaens GC, Systemic lupus erythematosus and pregnancy, Obstet Gynecol Surv, 44, pp. 585-591, (1989)

[7]

Meehan RT, Dorsey JK, Pregnancy among patients with systemic lupus erythematosus receiving immunosuppressive therapy, J Rheumatol, 14, pp. 252-258, (1987)

[8]

Mintz G., Niz J., Gutierrez G., Garcia-Alonso A., Karchmer, Prospective study of pregnancy in systemic lupus erythematosus. Results of a multidisciplinary approach, J Rheumatol, 13, pp. 732-739, (1986)

[9]

Lockshin MD, Pregnancy does not cause systemic lupus erythematosus to worsen, Arthritis Rheum, 32, pp. 665-670, (1989)

[10]

Lockshin MD, Reinitz E., Druzin ML, Murrman M., Estes D., Case control prospective study demonstrating absence of lupus exacerbation during or after pregnancy, Am J Med, 77, pp. 893-898, (1984)

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