ADSORPTION OF BOVINE SERUM-ALBUMIN ON POSITIVELY AND NEGATIVELY CHARGED MICROCAPSULES

被引：11

作者：

MURAMATSU, N

KONDO, T

机构：

[1] SCI UNIV TOKYO,FAC PHARMACEUT SCI,12 ICHIGAYA FUNAGAWARA MACHI,SHINJUKU KU,TOKYO 162,JAPAN

[2] SCI UNIV TOKYO,INST COLLOID & INTERFACE SCI,TOKYO 162,JAPAN

来源：

JOURNAL OF COLLOID AND INTERFACE SCIENCE | 1992年 / 153卷 / 01期

关键词：

D O I：

10.1016/0021-9797(92)90294-V

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Adsorption of bovine serum albumin onto positively and negatively charged particles, microcapsules, was examined in view of electrical interactions. The overall adsorption profiles were governed by the sign of net charge of the protein and the adsorbent, but in the immediate vicinity of the microcapsule surface it was suggested that the charge balance could affect the adsorption and the molecular structure of BSA. The amount of adsorption was smallest on the surface which has an isoelectric point similar to that of BSA, indicating again the important role in adsorption of the charge balance for both BSA molecules and the adsorbent surface. © 1992.

引用

页码：23 / 29

页数：7

共 17 条

[1]

ANDRADE J, 1985, SURFACE INTERFACIAL, V2

[2] THE BEHAVIOR OF SOME MODEL PROTEINS AT SOLID LIQUID INTERFACES .1. ADSORPTION FROM SINGLE PROTEIN SOLUTIONS [J].