THE STRUCTURE OF THE O-SPECIFIC CHAIN OF LEGIONELLA-PNEUMOPHILA SEROGROUP-1 LIPOPOLYSACCHARIDE

被引：107

作者：

KNIREL, YA

RIETSCHEL, ET

MARRE, R

ZAHRINGER, U

机构：

[1] FORSCHUNGSINST BORSTEL, INST EXPTL BIOL & MED, D-23845 BORSTEL, GERMANY

[2] ND ZELINSKII INST ORGAN CHEM, MOSCOW 117913, RUSSIA

[3] UNIV ULM, INST MIKROBIOL, BAKTERIOL ABT, W-7900 ULM, GERMANY

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 1994年 / 221卷 / 01期

关键词：

D O I：

10.1111/j.1432-1033.1994.tb18734.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The O-polysaccharide chain of Legionella pneumophila Philadelphia strain 1 (serogroup 1) lipopolysaccharide was investigated by means of H-1- and C-13-NMR spectroscopy, and chemical analysis. It was found to consist of an alpha-(2-->4) interlinked homopolymer of a 5-acetamidino-7-acetamido-8-O-acetyl-3,5,7,9-tetradeoxy-nonulosonic acid possessing most likely the D-glycero-L-galacto configuration, representing the first example of an acidic homopolymer of a higher sugar of this class. The ladder-like banding pattern exhibiting Small distances between individual bands in the SDS/PAGE is compatible with a monosaccharide repeating unit.

引用

页码：239 / 245

页数：7

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