A GENETIC-MAP OF MICROSATELLITE MARKERS ON RAT CHROMOSOME-7

被引：10

作者：

DU, Y ^{[1
]}

REMMERS, EF ^{[1
]}

ZHA, H ^{[1
]}

GOLDMUNTZ, EA ^{[1
]}

SZPIRER, J ^{[1
]}

SZPIRER, C ^{[1
]}

WILDER, RL ^{[1
]}

机构：

[1] FREE UNIV BRUSSELS,DEPT BIOL MOLEC,B-1640 RHODE ST GENESE,BELGIUM

来源：

MAMMALIAN GENOME | 1995年 / 6卷 / 04期

关键词：

D O I：

10.1007/BF00352420

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Nine microsatellite loci were mapped to rat Chromosome (Chr) 7 by genetic linkage and somatic cell hybrid analysis. These loci include the gene encoding a member of the IID subfamily of cytochrome P450 (Cyp2d), a gene with repetitive sequences expressed during myotube formation (D7Arble), four anonymous loci, D7Arb81, D7Arb208, D7Arb569, D7Arb609a, and three DNA loci defined by MapPair(TM) markers R245, R513, and R1071. The nine loci were all identified by PCR-based microsatellite polymorphism analysis and were characterized in 40 F-2 intercross progeny of Fischer (F344/N) and Lewis (LEW/N) rats for segregation analysis. These markers formed a single linkage group spanning 76.8 cM with the following order and distances: D7Arb569-11.4 cM-D7Arb81-9.7 cM-R513-2.6 cM-Cyp2d-0.0 cM-R245-1.3 cM-D7Arble-10.4 cM-R1071-15.9 cM-D7Arb609a-15.4 cM-D7Arb208. Physical mapping of Cyp2d by somatic cell hybrid analysis allowed us to assign this linkage group to rat Chr 7. For each marker, two to six alleles were detected in a panel of 16 inbred rat strains (ACI/N, BN/SsN, BUF/N, DA/Bkl, F344/N, LER/N, LEW/N, LOU/MN, MNR/N, MR/N, SHR/N, SR/Jr, SS/Jr, WBB1/N, WBB2/N, WKY/N).

引用

页码：295 / 298

页数：4

共 19 条

[1] SURVEY OF HUMAN AND RAT MICROSATELLITES
BECKMANN, JS
WEBER, JL
[J]. GENOMICS, 1992, 12 (04) : 627 - 631
[2] CHUNG SY, 1993, MAMM GENOME, V4, P527
[3] DENDUNNEN JT, 1987, NUCLEIC ACIDS RES, V15, P2772
[4] A COMPREHENSIVE SET OF SEQUENCE-ANALYSIS PROGRAMS FOR THE VAX
DEVEREUX, J
HAEBERLI, P
SMITHIES, O
[J]. NUCLEIC ACIDS RESEARCH, 1984, 12 (01) : 387 - 395
[5] GENETIC-MAP OF 8 MICROSATELLITE MARKERS COMPRISING 2 LINKAGE GROUPS ON RAT CHROMOSOME-6
DU, Y
REMMERS, EF
ZHA, H
GOLDMUNTZ, EA
MATHERN, P
CROFFORD, LJ
SZPIRER, J
SZPIRER, C
WILDER, RL
[J]. CYTOGENETICS AND CELL GENETICS, 1995, 68 (1-2): : 107 - 111
[6] Green EL, 1981, GENETICS PROBABILITY, P77
[7] REGULATED EXPRESSION OF REPETITIVE SEQUENCES INCLUDING THE IDENTIFIER SEQUENCE DURING MYOTUBE FORMATION IN CULTURE
HERGET, T
REICH, M
STUBER, K
STARZINSKIPOWITZ, A
[J]. EMBO JOURNAL, 1986, 5 (04) : 659 - 664
[8] POLYMORPHIC MICROSATELLITE LOCI OF THE RAT (RATTUS-NORVEGICUS)
KUNIEDA, T
KOBAYASHI, E
TACHIBANA, M
IKADAI, H
IMAMICHI, T
[J]. MAMMALIAN GENOME, 1992, 3 (10) : 564 - 567
[9] LANDER E S, 1987, Genomics, V1, P174, DOI 10.1016/0888-7543(87)90010-3
[10] COMPUTERIZED ESTIMATION OF SIZE OF NUCLEIC-ACID FRAGMENTS USING THE 4-PARAMETER LOGISTIC MODEL
OERTER, KE
MUNSON, PJ
MCBRIDE, WO
RODBARD, D
[J]. ANALYTICAL BIOCHEMISTRY, 1990, 189 (02) : 235 - 243

← 1 2 →