OCCURRENCE OF CYTOCHROME-P-450 AND ARYL-HYDROCARBON HYDROXYLASE-ACTIVITY IN DROSOPHILA-MELANOGASTER MICROSOMES, AND IMPORTANCE OF THIS METABOLIZING CAPACITY FOR SCREENING OF CARCINOGENIC AND MUTAGENIC PROPERTIES OF FOREIGN COMPOUNDS

被引：65

作者：

BAARS, AJ

ZIJLSTRA, JA

VOGEL, E

BREIMER, DD

机构：

[1] STATE UNIV LEIDEN, SUBFAC PHARM, DEPT PHARMACOL, LEIDEN, NETHERLANDS

[2] STATE UNIV LEIDEN, FAC MED, DEPT RADIAT GENET & CHEM MUTAGENESIS, LEIDEN, NETHERLANDS

来源：

MUTATION RESEARCH | 1977年 / 44卷 / 02期

关键词：

D O I：

10.1016/0027-5107(77)90083-5

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

引用

页码：257 / 267

页数：11

共 37 条

[1] INSECT CYTOCHROME-P-450 [J].

AGOSIN, M .

MOLECULAR AND CELLULAR BIOCHEMISTRY, 1976, 12 (01) :33-44

[2] CARCINOGENS ARE MUTAGENS - SIMPLE TEST SYSTEM COMBINING LIVER HOMOGENATES FOR ACTIVATION AND BACTERIA FOR DETECTION [J].

AMES, BN ;

DURSTON, WE ;

YAMASAKI, E ;

LEE, FD .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1973, 70 (08) :2281-2285

[3]

BENKE G M, 1971, Pesticide Biochemistry and Physiology, V1, P19, DOI 10.1016/0048-3575(71)90208-2

[4] MICROSOMAL OXIDASES IN A COCKROACH, GROMPHADORHINA-PORTENTOSA ORTHOPTERA-BLABERIDAE [J].

BENKE, GM ;

WILKINSON, CF ;

TELFORD, JN .

JOURNAL OF ECONOMIC ENTOMOLOGY, 1972, 65 (05) :1221-+

[5] MICROSOMAL ENZYME-INHIBITOR IN GUT CONTENTS OF HOUSE CRICKET (ACHETA-DOMESTICUS) [J].

BRATTSTEN, LB ;

WILKINSON, CF .

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY, 1973, 45 (1B) :59-70

[6] SHORT-TERM SCREENING-TESTS FOR CARCINOGENS [J].

BRIDGES, BA .

NATURE, 1976, 261 (5557) :195-200

[7]

CASSIDA JE, 1969, MICROSOMES DRUG OXID, P517

[8] KINETIC PARAMETERS OF DRUG-METABOLIZING ENZYMES IN CA2+ - SEDIMENTED MICROSOMES FROM RAT-LIVER [J].

CINTI, DL ;

SCHENKMAN, JB ;

MOLDEUS, P .

BIOCHEMICAL PHARMACOLOGY, 1972, 21 (24) :3249-+

[9] MUTAGENIC ACTIVITY OF THE ALKALOID HELIOTRINE IN DROSOPHILA [J].

CLARK, AM .

NATURE, 1959, 183 (4663) :731-732

[10]

DEMEREC M, 1949, CARNEGIE I WASH YB, V48, P156

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