BENZOCAINE-INDUCED METHEMOGLOBINEMIA

被引：23

作者：

POTTER, JL

HILLMAN, JV

机构：

[1] Departments of Pathology and Pediatrics, Children's Hospital Medical Center of Akron, Akron, OH

来源：

JACEP-JOURNAL OF THE AMERICAN COLLEGE OF EMERGENCY PHYSICIANS | 1979年 / 8卷 / 01期

关键词：

benzocaine ingestion; methemoglobinemia; benzocaine;

D O I：

10.1016/S0361-1124(79)80446-3

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Intense cyanosis in a previously well, 30-month-old, white girl was found to be due to the ingestion of benzocaine. A wide variety of chemical compounds present in many proprietary products, when ingested, can cause this presentation in individuals with structurally normal hemoglobin and normal activity of methemoglobin reductase. The phenomenon appears to be dose-related. Immediate recognition and initiation of appropriate therapy will effect a rapid reversal of the methemoglobinemia, and in some cases, may be life-saving. Caution should be exercised in the use of benzocaine-containing preparations. © 1979 American College of Emergency Physicians.

引用

页码：26 / 27

页数：2

共 16 条

[1] Mentzen, Methemoglobinemia, Pediatrics, (1977)
[2] Done, The toxic emergency, Emergency Medicine, (1975)
[3] Goluboff, MacFayden, Methemoglobinemia in an infant
[4] associated with application of a tar-benzocaine ointment, Pediatrics, 21, (1955)
[5] Wolff, Methemoglobinemia due to benzocaine, Pediatrics, 20, (1957)
[6] Peterson, Acquired methemoglobinemia in an infant due to benzocaine suppository, N Engl J Med, 263, (1960)
[7] Haggerty, Blue Baby Due to Methemoglobinemia, New England Journal of Medicine, 267, (1962)
[8] Hughes, Infantile methemoglobinemia due to benzocaine suppository, J Pediatr, 66, (1965)
[9] Townes, Geertsma, Benzocaine-induced methemoglobinemia, Am J Dis Child, 131, (1977)
[10] Physicians' Desk Reference, (1978)

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