SERUM TOTAL FREE-RADICAL TRAPPING ABILITY IN ACUTE MYOCARDIAL-INFARCTION

被引：33

作者：

MULHOLLAND, CW ^{[1
]}

STRAIN, JJ ^{[1
]}

机构：

[1] UNIV ULSTER, BIOMED SCI RES CTR, CROMORE RD, COLERAINE BT52 1SA, NORTH IRELAND

来源：

CLINICAL BIOCHEMISTRY | 1991年 / 24卷 / 05期

关键词：

ACUTE MYOCARDIAL INFARCTION; ANTIOXIDANTS; VITAMIN-E; VITAMIN-C; MYOCARDIAL REPERFUSION;

D O I：

10.1016/S0009-9120(05)80020-7

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Serum total free radical trapping abilities (TRAP experimental) were measured in 15 patients with acute myocardial infarction (AMI) and compared to sex- and age-matched controls. TRAP experimental values were significantly lower (p < 0.01) in the AMI group. Theoretical trapping abilities were also calculated and compared with experimentally derived values. In the AMI group there was no significant difference between the experimental and calculated TRAP, but in the control group experimental values were significantly higher (p < 0.01) than calculated values. In the control group regression analysis revealed that alpha-tocopherol and ascorbate taken together most closely explained the radical trapping ability of sera, with a regression equation: TRAP experimental = 562.9 + 2.082 (alpha-tocopherol + ascorbate). In the AMI group no relationship between the serum antioxidants and TRAP experimental was observed.

引用

页码：437 / 441

页数：5

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