MYOD1 PROTEIN EXPRESSION IN ALVEOLAR SOFT PART SARCOMA AS CONFIRMATORY EVIDENCE OF ITS SKELETAL-MUSCLE NATURE

被引：84

作者：

ROSAI, J

DIAS, P

PARHAM, DM

SHAPIRO, DN

HOUGHTON, P

机构：

[1] ST JUDE CHILDRENS RES HOSP, DEPT BIOCHEM & CLIN PHARMACOL, MEMPHIS, TN 38101 USA

[2] ST JUDE CHILDRENS RES HOSP, DEPT PATHOL & LAB MED, MEMPHIS, TN 38101 USA

[3] ST JUDE CHILDRENS RES HOSP, DEPT SAKYO KU, MEMPHIS, TN 38101 USA

[4] UNIV TENNESSEE, CTR HLTH SCI, DEPT PATHOL, MEMPHIS, TN 38163 USA

[5] UNIV TENNESSEE, CTR HLTH SCI, DEPT PEDIAT, MEMPHIS, TN 38163 USA

[6] YALE UNIV, SCH MED, DEPT PATHOL, NEW HAVEN, CT 06510 USA

来源：

AMERICAN JOURNAL OF SURGICAL PATHOLOGY | 1991年 / 15卷 / 10期

关键词：

ALVEOLAR SOFT PART SARCOMA; SKELETAL MUSCLE; SOFT TISSUE TUMORS; MYOD1; PROTEIN;

D O I：

10.1097/00000478-199110000-00008

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

A typical case of alveolar soft part sarcoma was found to express in a strong and widespread fashion the marker MyoD1 protein. This nuclear phosphoprotein is the product of a regulatory gene that controls the commitment of a cell to myogenic lineage; it therefore provides strong and perhaps definitive evidence in support of the skeletal muscle nature of this enigmatic neoplasm.

引用

页码：974 / 981

页数：8

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2-9

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