DIASTEREOSELECTIVE AND ENANTIOSELECTIVE MICHAEL ADDITION INITIATED CYCLIZATIONS TO TRANS-SUBSTITUTED CYCLOPENTANECARBOXYLATES

被引：26

作者：

ENDERS, D

SCHERER, HJ

RAABE, G

机构：

[1] Institut für Organische Chemie der Technischen Hochschule, Aachen, W-5100

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 1991年 / 30卷 / 12期

关键词：

D O I：

10.1002/anie.199116641

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Diastereomeric and enantiomeric excesses of greater than 95 % were achieved in the preparation of the cyclopentanecarboxylate 3 by asymmetric MIRC (Michael initiated ring closure) reactions of the hydrazones 1 with the unsaturated brominated ester 2. The de and ee values were determined by gas chromatography and in NMR experiments. RMe, nBu, iBu, Ph, p‐BrC6H4. (Figure Presented.) Copyright © 1991 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：1664 / 1666

页数：3

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