MOLECULAR-CLONING OF 2 NOVEL PROTEIN-KINASE GENES FROM ARABIDOPSIS-THALIANA

被引:38
作者
MORAN, TV [1 ]
WALKER, JC [1 ]
机构
[1] UNIV MISSOURI, DIV BIOL SCI, 105 TUCKER HALL, COLUMBIA, MO 65211 USA
关键词
PROTEIN PHOSPHORYLATION; ONCOGENE; GENE STRUCTURE; GENE EXPRESSION;
D O I
10.1016/0167-4781(93)90031-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
We have isolated two novel protein kinase genes, MHK and NAK, from the plant Arabidopsis thaliana by using low stringency hybridization with the catalytic domain of a putative plant receptor protein kinase. Sequence analysis of the cDNAs reveals that MHK is a member of the cdc2+ family of protein kinases and is particularly similar to the mak gene of rats; mak encodes a protein kinase that may play a role in spermatogenesis. NAK encodes a candidate protein kinase that is similar to the oncogenes met and abl. The homology that these two Arabidopsis genes share with other protein kinases suggests that they may play a role in the regulation of plant growth and development.
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页码:9 / 14
页数:6
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