DYNAMIC BEHAVIOR OF AG-110M IN SHEEP TISSUES

The transfer coefficient of Ag-110m to a range of sheep tissues and its biological half-life in these tissues has been determined. Liver was shown to be the major site of Ag-110m deposition and retention, with a transfer coefficient of F(f) 7.1 d kg-1 and a biological half-life of 79 d. These results also suggest that previous estimates of the transfer of silver to muscle were too high, although further work would be required to confirm this. There is a need for accurate data which can be used to predict the transfer of Ag-110m to food-producing animals.