N-ACETYLASPARTATE AND EPILEPSY

被引：35

作者：

GADIAN, DG

机构：

[1] Radiology and Physics Unit, Institute of Child Health, London, WC1N 1EH

来源：

MAGNETIC RESONANCE IMAGING | 1995年 / 13卷 / 08期

基金：

英国惠康基金;

关键词：

MAGNETIC RESONANCE SPECTROSCOPY; N-ACETYLASPARTATE; TEMPORAL LOBE; EPILEPSY;

D O I：

10.1016/0730-725X(95)02032-O

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Proton magnetic resonance spectra include signals from N-acetylaspartate, creatine + phosphocreatine, and choline-containing compounds, Abnormalities in these signals can be used in the assessment of patients with intractable epilepsy. In particular, they provide a means of identifying metabolic abnormalities within the temporal lobes, detecting bilateral and diffuse pathology, and aiding lateralization of the seizure focus. The pathology demonstrated on MRS can also be related to cognitive dysfunction.

引用

页码：1193 / 1195

页数：3

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