PHOSPHONOFORMATE AND PHOSPHONOACETATE DERIVATIVES OF 5-SUBSTITUTED 2'-DEOXYURIDINES - SYNTHESIS AND ANTIVIRAL ACTIVITY

被引：27

作者：

GRIENGL, H

HAYDEN, W

PENN, G

DECLERCQ, E

ROSENWIRTH, B

机构：

[1] CATHOLIC UNIV LEUVEN,REGA INST MED RES,B-3000 LOUVAIN,BELGIUM

[2] SANDOZ FORSCHUNGSINST,A-1235 VIENNA,AUSTRIA

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1988年 / 31卷 / 09期

关键词：

D O I：

10.1021/jm00117a026

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：1831 / 1839

页数：9

共 31 条

[1] COMBINED CHEMOTHERAPY OF CUTANEOUS HERPES-SIMPLEX INFECTION OF THE GUINEA-PIG [J].

BURKHARDT, U ;

WIGAND, R .

JOURNAL OF MEDICAL VIROLOGY, 1983, 12 (02) :137-147

[2]

COEN D, 1980, P NAT ACAD SCI US, V77, P2273

[3] RESISTANCE OF HERPES-SIMPLEX VIRUS TO ACYCLOGUANOSINE - GENETIC AND PHYSICAL ANALYSIS [J].

CRUMPACKER, CS ;

CHARTRAND, P ;

SUBAKSHARPE, JH ;

WILKIE, NM .

VIROLOGY, 1980, 105 (01) :171-184

[4] RESISTANCE OF HERPES-SIMPLEX VIRUS TO ADENINE-ARABINOSIDE AND E-5-(2-BROMOVINYL)-2'-DEOXYURIDINE - A PHYSICAL ANALYSIS [J].

CRUMPACKER, CS ;

SCHNIPPER, LE ;

KOWALSKY, PN ;

SHERMAN, DM .

JOURNAL OF INFECTIOUS DISEASES, 1982, 146 (02) :167-172

[5] TREATMENT OF EXPERIMENTAL HERPES-SIMPLEX VIRUS ENCEPHALITIS WITH (E)-5-(2-BROMOVINYL)-2'-DEOXYURIDINE IN MICE [J].

DECLERCQ, E ;

ZHANG, ZX .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1982, 22 (03) :421-425

[6] SELECTIVE INVITRO AND INVIVO ACTIVITIES OF 5-(2-HALOALKYL)PYRIMIDINE NUCLEOSIDE ANALOGS, PARTICULARLY 5-(2-CHLOROETHYL)-2'-DEOXYURIDINE, AGAINST HERPES-SIMPLEX VIRUS [J].

DECLERCQ, E ;

ROSENWIRTH, B .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1985, 28 (02) :246-251

[7]

DECLERCQ E, 1979, P NATL ACAD SCI USA, V76, P2947, DOI 10.1073/pnas.76.6.2947

[8] E-5-(2-BROMOVINYL)-2'-DEOXYURIDINE VS INTERFERON IN THE SYSTEMIC TREATMENT OF INFECTION WITH HERPES-SIMPLEX VIRUS OF ATHYMIC NUDE-MICE [J].

DECLERCQ, E ;

ZHANG, ZX ;

DESCAMPS, J ;

HUYGEN, K .

JOURNAL OF INFECTIOUS DISEASES, 1981, 143 (06) :846-852

[9]

DECLERCQ E, 1985, APPROACHES ANTIVIRAL, P57

[10] ACYCLOVIR-RESISTANT MUTANTS OF HERPES-SIMPLEX VIRUS TYPE-1 EXPRESS ALTERED DNA-POLYMERASE OR REDUCED ACYCLOVIR PHOSPHORYLATING ACTIVITIES [J].

FURMAN, PA ;

COEN, DM ;

STCLAIR, MH ;

SCHAFFER, PA .

JOURNAL OF VIROLOGY, 1981, 40 (03) :936-941

← 1 2 3 4 →