Variations on a theme: the family of FAD-dependent NAD(P)H-(disulphide)-oxidoreductases

被引：41

作者：

Pai, Emil F. ^{[1
]}

机构：

[1] Max Planck Inst Med Forsch, Heidelberg, Germany

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1991年 / 1卷 / 05期

关键词：

D O I：

10.1016/0959-440X(91)90181-R

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The term protein 'family' has been used to describe groups of related enzymes that share structural and mechanistic properties. A beautiful example for such an ensemble is the FAD-dependent NAD(P)H-(disulphide)-oxidoreductases. Crystal structures for several family members have recently been determined. They provide interesting clues as to how in evolution a proven form can be changed to satisfy new requirements.

引用

页码：796 / 803

页数：8

共 54 条

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