MUTAGENIC ACTIVITY OF MARIHUANA SMOKE CONDENSATES

被引：57

作者：

BUSCH, FW ^{[1
]}

SEID, DA ^{[1
]}

WEI, ET ^{[1
]}

机构：

[1] UNIV CALIF BERKELEY, SCH PUBL HLTH, BERKELEY, CA 94720 USA

来源：

CANCER LETTERS | 1979年 / 6卷 / 06期

关键词：

D O I：

10.1016/S0304-3835(79)80088-9

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Smoke condensates prepared from marihuana cigarettes were mutagenic in strain TA98 of the Ames Salmonella/microsome test, a short-term bioassay which estimates the mutagenic and carcinogenic potential of some chemicals. The mutagens in marihuana smoke condensates required liver enzymes to be activated. The specific mutagenic activity of marihuana smoke condensates were similar to that of tobacco smoke condensates prepared from American cigarettes. Fractionation studies of the marihuana smoke condensates showed that basic components accounted for 76% of the recovered mutagenic activity. © 1979 Elsevier/North-Holland Scientific Publishers Ltd., All rights reserved.

引用

页码：319 / 324

页数：6

共 18 条

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