METAL-PROMOTED THIYL RADICAL CYCLIZATIONS IN BETA-LACTAM ANTIBIOTICS

被引：20

作者：

CABRI, W ^{[1
]}

CANDIANI, I ^{[1
]}

BEDESCHI, A ^{[1
]}

SANTI, R ^{[1
]}

机构：

[1] IST G DONEGANI SPA MONTEDISON,I-28100 NOVARA,ITALY

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 33期

关键词：

THIOL; RADICAL CYCLIZATION; IRON; MANGANESE;

D O I：

10.1016/S0040-4039(00)61285-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Intramolecular thiyl radical addition to a double bond promoted by Fe(III) and Mn(III) is described. The stabilized radical intermediate afforded by subsequent hydrogen abstraction cephams 4 and 5.

引用

页码：4783 / 4786

页数：4

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