CELLULAR-IMMUNITY IN INTERSTITIAL NEPHROPATHY

被引：3

作者：

MEEUS, F

ROSSERT, J

DRUET, P

机构：

[1] Department of Nephrology and INSERM U28, Hopital Broussals, 75014, Paris

来源：

RENAL FAILURE | 1993年 / 15卷 / 03期

关键词：

D O I：

10.3109/08860229309054939

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Inflammatory tubulointestitial nephritis (TIN), either as a primary or as a secondary event, plays an essential role in the development of all forms of chronic renal failure. Experimental models of TIN should help in understanding TIN in humans. As in experimental glomerulopathies, the target antigen can be a kidney structural antigen, from the tubular basement membrane (TBM) or not, or a foreign antigen. While some models are due to deposits of free antibodies or circulating immune complexes, many others involve cell-mediated immunity. This last aspect explains the importance and the originality of experimental TIN.

引用

页码：325 / 329

页数：5

共 28 条

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