PHOSPHORYLATION OF NEUROTROPIC ALPHAHERPESVIRUS ENVELOPE GLYCOPROTEINS - HERPES-SIMPLEX VIRUS TYPE-2 GE2 AND PSEUDORABIES VIRUS GI

I have examined the state of phosphorylation of the envelope glycoproteins of two neurotropic herpesviruses, HSV-2 and PRV. HSV-2 gE2 and PRV gl, which are the homologues to HSV-1 gE, were found to be phosphorylated and phosphoaminoacid analysis revealed that both contained phosphoserine. These findings are consistent with a conserved phosphorylation of the glycoprotein homologues to HSV gE among the neurotropic alphaherpesviruses. © 1993 Academic Press Inc.