LOSS OF REACTIVITY OF A MYELOMA TUMOR WITH H-2 COMPATIBLE THYMUS-DERIVED LYMPHOCYTES

被引：7

作者：

HALE, AH

PAULUS, LK

机构：

[1] Department of Microbiology and Immunology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem

来源：

CELLULAR IMMUNOLOGY | 1979年 / 46卷 / 02期

关键词：

D O I：

10.1016/0008-8749(79)90421-0

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

It was previously shown that MOPC-315-EL, a subline of the BALB/c myeloma tumor MOPC-315, reversibly alters its reactivity with T cells that recognize H-2d, 2,4,6-trinitrophenyl, and minor histocompatibility antigens. This report demonstrates (a) that CTLs directed against vesicular stomatitis virus and Sendai virus are unable to recognize viral antigens associated with the unreactive tumor cell, and (b) that incorporation of Sendai virus antigens into the same membrane as the H-2 gene products is required for effective recognition by cytotoxic T lymphocytes. © 1979.

引用

页码：337 / 347

页数：11

共 12 条

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