2 ARYLAMIDASES FROM HUMAN LIVER AND THEIR KININ-CONVERTING ACTIVITY

被引：13

作者：

FREITAS, JO

GUIMARAES, JA

BORGES, DR

PRADO, JL

机构：

[1] Department of Biochemistry and Pharmacology, Escola Paulista de Medicina, 01000 São Paulo, SP

来源：

INTERNATIONAL JOURNAL OF BIOCHEMISTRY | 1979年 / 10卷 / 01期

关键词：

D O I：

10.1016/0020-711X(79)90143-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. 1. Two arylamidases, called B and N, were found in human liver homogenates. 2. 2. Arylamidase N, purified 300-fold, MW 200,000, converts lysylbradykinin into bradykinin at a rate higher than 1.53 μniole/min per mg protein, and does not depend on chloride ions. 3. 3. Arylamidase B, unstable, is a chloride dependent arylamidase and has no kinin-converting activity. 4. 4. Comparative hydrolysis rates of some aminoacyl-β-naphthylamides and other properties also show that they are different enzymes. © 1979.

引用

页码：81 / 89

页数：9

共 17 条

[1] ESTIMATION OF MOLECULAR WEIGHTS OF PROTEINS BY SEPHADEX GEL-FILTRATION
ANDREWS, P
[J]. BIOCHEMICAL JOURNAL, 1964, 91 (02) : 222 - +
[2] PHOTOMETRIC ANALYSIS OF PHOSPHATE ROCK
BARTON, CJ
[J]. ANALYTICAL CHEMISTRY, 1948, 20 (11) : 1068 - 1073
[3] ARYLAMIDASE OF HUMAN LIVER
BEHAL, FJ
LITTLE, GH
KLEIN, RA
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1969, 178 (01) : 118 - &
[4] CHARACTERIZATION OF A KININ-CONVERTING ARYLAMINOPEPTIDASE FROM HUMAN LIVER
BORGES, DR
PRADO, JL
GUIMARAES, JA
[J]. NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1974, 281 (04) : 403 - 414
[5] KININ-CONVERTING AMINOPEPTIDASE FROM HUMAN URINE PARTIAL-PURIFICATION AND PROPERTIES
BRANDI, CMW
PRADO, ES
PRADO, MJBA
PRADO, JL
[J]. INTERNATIONAL JOURNAL OF BIOCHEMISTRY, 1976, 7 (6-7): : 335 - 341
[6] GOLDBARG JA, 1958, CANCER, V11, P283, DOI 10.1002/1097-0142(195803/04)11:2<283::AID-CNCR2820110209>3.0.CO
[7] 2-8
[8] KININ-CONVERTING AMINOPEPTIDASE FROM HUMAN-SERUM
GUIMARAES, JA
BORGES, DR
PRADO, ES
PRADO, JL
[J]. BIOCHEMICAL PHARMACOLOGY, 1973, 22 (24) : 3157 - 3172
[9] Little G H, 1976, Methods Enzymol, V45, P495
[10] HUMAN LIVER ARYLAMIDASE - MOLECULAR WEIGHT AND SUBUNIT STRUCTURE
LITTLE, GH
BEHAL, FJ
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1971, 243 (02) : 312 - &

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