DISPARATE NA+-REQUIREMENT OF TAUROCHOLATE AND INDOCYANINE GREEN UPTAKE BY ISOLATED HEPATOCYTES

被引：31

作者：

MINDER, E

PAUMGARTNER, G

机构：

[1] Department of Clinical Pharmacology, University of Berne, Berne, CH-3010

来源：

EXPERIENTIA | 1979年 / 35卷 / 07期

关键词：

D O I：

10.1007/BF01955131

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Uptake of both taurocholate and indocyanine green (ICG) by isolated rat hepatocytes was saturable and obeyed Michaelis-Menten kinetics. Only uptake of taurocholate exhibited Na+-dependence, a phenomenon compatible with active membrane transport. These findings suggest that the mechanisms responsible for hepatocellular uptake of bile acids and anionic dyes differ fundamentally. © 1979 Birkhäuser Verlag.

引用

页码：888 / 890

页数：3

共 19 条

[1] EFFECT OF ALBUMIN ON BILE-ACID UPTAKE BY ISOLATED RAT HEPATOCYTES - THERE A COMMON BILE-ACID CARRIER [J].