DETECTION OF CLASS-II ANTIGENS ON HUMAN NASAL CARTILAGE

被引：11

作者：

BUJIA, J ^{[1
]}

WILMES, E ^{[1
]}

KROMBACH, F ^{[1
]}

HAMMER, C ^{[1
]}

KASTENBAUER, E ^{[1
]}

机构：

[1] UNIV MUNICH,KLINIKUM GROSSHADERN,DEPT OTORHINOLARYNGOL,W-8000 MUNICH 70,GERMANY

来源：

AMERICAN JOURNAL OF OTOLARYNGOLOGY | 1990年 / 11卷 / 05期

关键词：

cartilage transplantation; class II antigens; flow cytometric analysis; immunohistochemistry;

D O I：

10.1016/0196-0709(90)90065-4

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

The presence and distribution of class II antigens on human nasal cartilage was investigated using monoclonal antibodies directed against HLA-DR, HLA-DP, and HLA-DQ molecules. Tissue sections and chondrocytes in suspension were prepared for immunoperoxidase staining and flow cytometric analysis. Class II antigens were detected primarily on the perichondrium. In contrast, chondrocytes, either isolated or in tissue sections, were completely negative, suggesting that cells of the perichondrium, may, by themselves, be capable of initiating a rejection process. © 1990.

引用

页码：339 / 344

页数：6

共 15 条

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