ENDOMETRIOSIS IN MONOZYGOTIC TWINS

Objective. To study the reproductive and medical history of monozygotic twin sisters and mothers of patients with endometriosis. Material and Methods. Among 515 patients with endometriosis, eight had a monozygotic twin sister all of whom had had a gynecological laparoscopy or laparotomy. In addition, five of their mothers had had a laparotomy. Details about these 13 relatives were obtained either from medical records (ten cases) or by unmistakable reports from the proband (three cases). Result. Six of the monozygotic twin sisters (75%) also had symptomatic endometriosis compared with 3.8% among other types of sisters (p<0.0005). Three of the mothers (38%) had either endometriosis or adenomyosis. Conclusion. This study gives support to the assumption that endometriosis has a genetic trait.