UP-REGULATION OF CALRETININ IN THE SUPRAOPTIC NUCLEUS OF THE RAT AFTER CHRONIC SALT LOADING

被引：5

作者：

ARAI, R ^{[1
]}

JACOBOWITZ, DM ^{[1
]}

NAGATSU, I ^{[1
]}

机构：

[1] NIMH,CLIN SCI LAB,BETHESDA,MD 20892

来源：

BRAIN RESEARCH | 1995年 / 673卷 / 02期

关键词：

CALCIUM-BINDING PROTEIN; CALCIUM BUFFER; CALRETININ; SALT LOADING; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; SUPRAOPTIC NUCLEUS; RAT;

D O I：

10.1016/0006-8993(95)00003-9

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We immunocytochemically examined the effect of chronic salt loading on the content of calretinin, a calcium-binding protein, in both the supraoptic nucleus and the magnocellular parts of the hypothalamic paraventricular nucleus. In control rats that were given water for drinking, the supraoptic nucleus contained a cluster of calretinin-stained cells. Drinking 2% sodium chloride solution for 7 days resulted in an increase of the staining intensity of calretinin in cells of the supraoptic nucleus. In both the control and salt-loaded rats, the magnocellular parts of the paraventricular nucleus were almost devoid of calretinin-labeled cells. It is suggested that expression of calretinin in cells of the supraoptic nucleus is up regulated by chronic salt loading.

引用

页码：339 / 343

页数：5

共 35 条

[1] IMMUNOHISTOCHEMICAL LOCALIZATION OF CALRETININ-CONTAINING, CALBINDIN-D28K-CONTAINING AND PARVALBUMIN-CONTAINING CELLS IN THE HYPOTHALAMIC PARAVENTRICULAR AND SUPRAOPTIC NUCLEI OF THE RAT [J].