DIFFUSION-COLLISION MODEL FOR PROTEIN FOLDING

被引：174

作者：

KARPLUS, M ^{[1
]}

WEAVER, DL ^{[1
]}

机构：

[1] TUFTS UNIV,DEPT PHYS,MEDFORD,MA 02155

来源：

BIOPOLYMERS | 1979年 / 18卷 / 06期

关键词：

D O I：

10.1002/bip.1979.360180608

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The basic equations for the elementary step in the diffusion–collision–coalescence model of protein folding are derived for the case of two radially diffusing spherical microdomains. Refinements and biological implications of the mechanism are considered; included are detailed discussions of the parameters of the model, the possibilities of rotational diffusion and surface diffusion in one or two dimensions, the nature of the microdomains, and the application of the model to protein unfolding. Copyright © 1979 John Wiley & Sons, Inc.

引用

页码：1421 / 1437

页数：17

共 27 条

[1]

Adam G., 1968, STRUCTURAL CHEM MOL, P198

[2]

Anfinsen C B, 1975, Adv Protein Chem, V29, P205, DOI 10.1016/S0065-3233(08)60413-1

[3] INTERMEDIATES IN PROTEIN FOLDING REACTIONS AND MECHANISM OF PROTEIN FOLDING [J].