SELECTIVE CLEAVAGE OF THE MYCINOSE SUGAR FROM THE MACROLIDE ANTIBIOTIC TYLOSIN - UNIQUE GLYCOSIDIC SCISSION

被引：11

作者：

NAGEL, AA

VINCENT, LA

机构：

[1] Pfizer Central Research, Groton, Connecticut

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1979年 / 44卷 / 12期

关键词：

D O I：

10.1021/jo01326a043

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A synthesis of 16-decarbomethoxy-20(S)-hydroxydihydrocatharanthine, an intermediate that has been converted to catharanthine in two stages, is available in seven steps from acrolein and 1, 4-dipivaloxy-1, 3-butadiene. © 1979, American Chemical Society. All rights reserved.

引用

页码：2050 / 2052

页数：3

共 15 条

[1] STUDIES ON METABOLIC PRODUCTS OF MICROORGANISMS .9. INFORMATION ON STRUCTURE OF TYLOSIN [J].