EMBEDDED OR NOT - HYDROPHOBIC SEQUENCES AND MEMBRANES

被引：21

作者：

SINGER, SJ

YAFFE, MP

机构：

[1] Department of Biology, University of California at San Diego, La Jolla

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1990年 / 15卷 / 10期

关键词：

D O I：

10.1016/0968-0004(90)90230-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The same translocation machinery appears to be responsible for both the translocation of soluble proteins across membranes and the insertion of integral membrane proteins into the bilayer. A single mechanism is proposed to accommodate these two functions. This model is also extended to explain the paradoxical translocation of mitochondrial and chloroplastic membrane proteins across one or more membranes before they are finally inserted into their target membranes. © 1990.

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页码：369 / 373

页数：5

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