HIGH-DIMENSIONAL SIMULATION OF THE SHAPE-SPACE MODEL FOR THE IMMUNE-SYSTEM

被引:31
作者
STAUFFER, D [1 ]
WEISBUCH, G [1 ]
机构
[1] ECOLE NORM SUPER,F-75231 PARIS 05,FRANCE
来源
PHYSICA A | 1992年 / 180卷 / 1-2期
关键词
D O I
10.1016/0378-4371(92)90107-2
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
For the reactions among the antibodies of the immune system, fighting against a foreign antigen, the recent model of de Boer, Segel and Perelson introduced a cellular automata approximation for the interaction of different types of B cells (bone marrow derived lymphocytes). In contrast to most physics models, here each lattice site interacts mainly with its mirror image (with respect to the lattice center) in the opposite part of the lattice. We simplify their model and then generalize it to include more than one or two shape-space parameters. Thus instead of simulating a chain or square lattice, we simulate a d-dimensional hypercubic lattice with dimension d up to 10. In particular, we check for the concentration of B cells and the stability against localized perturbations ("damage spreading").
引用
收藏
页码:42 / 52
页数:11
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