CRYSTALLIZATION AND PRELIMINARY DIFFRACTION DATA OF 2 MYOTOXINS ISOLATED FROM THE VENOMS OF BOTHROPS-ASPER (TERCIOPELO) AND BOTHROPS-NUMMIFER (JUMPING VIPER)

被引：18

作者：

ARNI, RK

GUTIERREZ, JM

机构：

[1] UNIV COSTA RICA,FAC MICROBIOL,INST CLODOMIRO PICADO,SAN JOSE,COSTA RICA

[2] UNIV ESTADUAL PAULISTA,INST BIOCIENCIAS,DEPT FIS,BR-15054 S JOSE RIO P,SP,BRAZIL

来源：

TOXICON | 1993年 / 31卷 / 08期

关键词：

D O I：

10.1016/0041-0101(93)90264-J

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Two myotoxins isolated from B. asper (myotoxin II) and B. nummifer (myotoxin I) snake venoms have been crystallized and their diffraction properties are described. These myotoxins are phospholipase A2 variants which lack enzymatic activity; B. asper myotoxin II is a lysine-49 phospholipase. Crystals were obtained at room temperature by standard hanging-drop vapour diffusion methods. Crystals diffracted to a resolution of 2.8 and 2.3 angstrom, respectively.

引用

页码：1061 / 1064

页数：4

共 26 条

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[2]

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