FUNCTIONAL RECOVERY OF STUNNED MYOCARDIUM IS GREATER WITH HALOTHANE THAN FENTANYL ANESTHESIA IN DOGS

被引：18

作者：

WHITE, JL ^{[1
]}

MYERS, AK ^{[1
]}

ANALOUEI, A ^{[1
]}

KIM, YD ^{[1
]}

机构：

[1] GEORGETOWN UNIV,MED CTR,WASHINGTON,DC 20007

来源：

BRITISH JOURNAL OF ANAESTHESIA | 1994年 / 73卷 / 02期

关键词：

ANESTHETICS; VOLATILE; HALOTHANE; ANALGESICS; OPIOID; FENTANYL; ANESTHESIA; GENERAL; HEART; PRESERVATION; ISCHEMIA; DOG;

D O I：

10.1093/bja/73.2.214

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

We have compared the effects of halothane or fentanyl on recovery of regional myocardial function in the postischaemic ventricle in dogs. The animals were followed for 120 min during reperfusion after 15-min of occlusion of the left anterior descending coronary artery. After 120 min of reperfusion, the fentanyl group had recovered only 54% and 50% of regional contractility and systolic shortening (P < 0.05), respectively, compared with halothane (63% and 86%). Intramyocardial tissue pressure was less than baseline 60 min after reperfusion in the fentanyl group (P < 0.05), whereas the halothane group had returned to control values. We conclude that halothane is more effective than fentanyl in attenuating regional myocardial dysfunction associated with transient episodes of ischaemia.

引用

页码：214 / 219

页数：6

共 47 条

[1] CANINE LEFT VENTRICULAR INTRAMYOCARDIAL PRESSURES [J].