STUDIES ON BLASTICIDIN A

被引：10

作者：

KONO, Y

TAKEUCHI, S

YONEHARA, H

机构：

[1] Institute of Applied Microbiology, University of Tokyo, Tokyo

来源：

JOURNAL OF ANTIBIOTICS | 1968年 / 21卷 / 07期

关键词：

D O I：

10.7164/antibiotics.21.433

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Blasticidin A (C51∼52H99∼101O23N1/2Ca, m. p. 165.5∼166.5°C, λmax 246 mμ and 298 mμ in 50 % methanol, [α]D24-31° in pyridine) was isolated in crystal form as calcium-chelated compound. The antibiotic shows activity against a variety of microorganisms with relatively less toxicity to mice orally. It seems to have some relationship to polyene macrolide antibiotics, but has marked differences in its properties. The isolation, purification and physicochemical properties of the antibiotic are described. © 1968, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

引用

页码：433 / &

共 8 条

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[2]

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