RELATIVE-RESIDUE SURFACE-ACCESSIBILITY PATTERNS REVEAL MYOGLOBIN AND CATALASE SIMILARITY

被引：2

作者：

COCKCROFT, VB ^{[1
]}

OSGUTHORPE, DJ ^{[1
]}

机构：

[1] UNIV BATH, MOLEC GRAPH UNIT, BATH BA2 7AY, AVON, ENGLAND

来源：

FEBS LETTERS | 1991年 / 293卷 / 1-2期

关键词：

RELATIVE-RESIDUE SURFACE-ACCESSIBILITY PATTERN; NONHOMOLOGOUS SIMILARITY; MYOGLOBIN; CATALASE;

D O I：

10.1016/0014-5793(91)81173-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A novel sliding-window search method using relative-residue surface-accessibility patterns identified extensive, but unsuspected, structural similarity over a 3-helix region in the C-terminus of the evolutionarily unrelated proteins sperm-whale myoglobin and beef liver catalase. This clear example of structural similarity between non-homologous proteins highlights the importance of relative-residue surface-accessibility patterns in understanding the local folded structure in proteins.

引用

页码：149 / 152

页数：4

共 14 条

[1] DETERMINANTS OF A PROTEIN FOLD - UNIQUE FEATURES OF THE GLOBIN AMINO-ACID-SEQUENCES [J].

BASHFORD, D ;

CHOTHIA, C ;

LESK, AM .

JOURNAL OF MOLECULAR BIOLOGY, 1987, 196 (01) :199-216

[2] IDENTIFICATION OF PROTEIN FOLDS - MATCHING HYDROPHOBICITY PATTERNS OF SEQUENCE SETS WITH SOLVENT ACCESSIBILITY PATTERNS OF KNOWN STRUCTURES [J].

BOWIE, JU ;

CLARKE, ND ;

PABO, CO ;

SAUER, RT .

PROTEINS-STRUCTURE FUNCTION AND GENETICS, 1990, 7 (03) :257-264

[3] DECIPHERING THE MESSAGE IN PROTEIN SEQUENCES - TOLERANCE TO AMINO-ACID SUBSTITUTIONS [J].

BOWIE, JU ;

REIDHAAROLSON, JF ;

LIM, WA ;

SAUER, RT .

SCIENCE, 1990, 247 (4948) :1306-1310

[4] THE CRYSTAL-STRUCTURE OF HUMAN DEOXYHEMOGLOBIN AT 1.74A RESOLUTION [J].

FERMI, G ;

PERUTZ, MF ;

SHAANAN, B ;

FOURME, R .

JOURNAL OF MOLECULAR BIOLOGY, 1984, 175 (02) :159-174

[5] HYDROPHOBIC CLUSTER-ANALYSIS - AN EFFICIENT NEW WAY TO COMPARE AND ANALYZE AMINO-ACID-SEQUENCES [J].

GABORIAUD, C ;

BISSERY, V ;

BENCHETRIT, T ;

MORNON, JP .

FEBS LETTERS, 1987, 224 (01) :149-155

[6] COMPARISON OF SOLVENT-INACCESSIBLE CORES OF HOMOLOGOUS PROTEINS - DEFINITIONS USEFUL FOR PROTEIN MODELING [J].

HUBBARD, TJP ;

BLUNDELL, TL .

PROTEIN ENGINEERING, 1987, 1 (03) :159-171

[7] A RELATIONAL DATABASE OF PROTEIN STRUCTURES DESIGNED FOR FLEXIBLE INQUIRIES ABOUT CONFORMATION [J].

ISLAM, SA ;

STERNBERG, MJE .

PROTEIN ENGINEERING, 1989, 2 (06) :431-442

[8] COMPARISON OF BEEF-LIVER AND PENICILLIUM-VITALE CATALASES [J].

MELIKADAMYAN, WR ;

BARYNIN, VV ;

VAGIN, AA ;

BORISOV, VV ;

VAINSHTEIN, BK ;

FITA, I ;

MURTHY, MRN ;

ROSSMANN, MG .

JOURNAL OF MOLECULAR BIOLOGY, 1986, 188 (01) :63-72

[9]

NEWCOMER ME, 1981, J BIOL CHEM, V256, P3213

[10] STRUCTURE AND FUNCTION OF HAEMOGLOBIN .2. SOME RELATIONS BETWEEN POLYPEPTIDE CHAIN CONFIGURATION AND AMINO ACID SEQUENCE [J].

PERUTZ, MF ;

KENDREW, JC ;

WATSON, HC .

JOURNAL OF MOLECULAR BIOLOGY, 1965, 13 (03) :669-&

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