ALPHA-MANNOSIDASE-CATALYZED SYNTHESIS OF NOVEL MANNO-OLIGOSACCHARIDES, LYXO-OLIGOSACCHARIDES, AND HETEROMANNO-OLIGOSACCHARIDES - A COMPARISON OF KINETICALLY AND THERMODYNAMICALLY MEDIATED APPROACHES

被引：26

作者：

RASTALL, RA

REES, NH

WAIT, R

ADLARD, MW

BUCKE, C

机构：

[1] CTR APPL MICROBIOL & RES,DIV PATHOL,SALISBURY,WILTS,ENGLAND

[2] THAMES POLYTECH,SCH BIOL & CHEM SCI,LONDON SE18 6PF,ENGLAND

来源：

ENZYME AND MICROBIAL TECHNOLOGY | 1992年 / 14卷 / 01期

关键词：

ALPHA-MANNOSIDASE; ENZYMES IN REVERSE; SYNTHESIS OF MANNO-OLIGOSACCHARIDES;

D O I：

10.1016/0141-0229(92)90026-K

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The alpha-mannosidase from jack bean has been used to catalyse the production of a range of novel oligosaccharides and oligosaccharide derivatives. p-Nitrophenyl oligosaccharide glycosides have been synthesized by glycosyl transfer from p-nitrophenyl alpha-mannoside donor to a range of p-nitrophenyl glycoside acceptors. Oligosaccharides have also been synthesized by the condensation of mannose with a range of mono- and oligosaccharide acceptors. The structures of oligosaccharides formed from mannose by condensation have been investigated by methylation analysis and NMR spectroscopy.

引用

页码：53 / 57

页数：5

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