THE UNUSUAL HYDRATION REACTIVITY OF ACYLKETENES - THEORETICAL AND EXPERIMENTAL STUDIES

被引：30

作者：

ALLEN, AD ^{[1
]}

MCALLISTER, MA ^{[1
]}

TIDWELL, TT ^{[1
]}

机构：

[1] UNIV TORONTO,DEPT CHEM,TORONTO M5S 1A1,ONTARIO,CANADA

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 07期

关键词：

D O I：

10.1016/S0040-4039(00)77499-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ab initio MO calculations indicate that the hydration of acylketenes may be assisted by complexation of the nucleophilic H2O molecule to the oxygen of the acyl substituent. Experimental studies for hydration of EtO2CC(Bu-t)=C=O (4) support this pathway.

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页码：1095 / 1098

页数：4

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