ANTIEMETIC PRINCIPLES OF MAGNOLIA-OBOVATA BARK AND ZINGIBER-OFFICINALE RHIZOME

被引：84

作者：

KAWAI, T ^{[1
]}

KINOSHITA, K ^{[1
]}

KOYAMA, K ^{[1
]}

TAKAHASHI, K ^{[1
]}

机构：

[1] MEIJI COLL PHARM,DEPT PHARMACOGNOSY & PHYTOCHEM,TANASHI,TOKYO 188,JAPAN

来源：

PLANTA MEDICA | 1994年 / 60卷 / 01期

关键词：

ANTIEMETICS; MAGNOLIA OBOVATA; MAGNOLIACEAE; ZINGIBER OFFICINALE; ZINGIBERACEAE; MAGNOLOL; HONOKIOL; SHOGAOL;

D O I：

10.1055/s-2006-959399

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Magnolol and honokiol, biphenyl compounds, were isolated as anti-emetic principles from the methanolic extract of Magnolia obovata bark. [6]-, [8]-, and [10]-shogaols and [6]-, [8]-, and [10]-gingerols were isolated from the methanolic extract of Zingiber officinale rhizome as anti-emetic principles. Some phenylpropanoids with allyl side-chains were found to show the same activity. They inhibited the emetic action induced by the oral administration of copper sulfate pentahydrate to leopard and ranid frogs.

引用

页码：17 / 20

页数：4

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