ON OCCURRENCE OF PHENOL AND STEROID SULPHOKINASES IN HUMAN GASTROINTESTINAL TRACT

被引：30

作者：

BOSTROM, H

BROMSTER, D

NORDENSTAM, H

WENGLE, B

机构：

[1] Departments of Medicine, Surgery and Pathology, Serafimerlasarettet, Karolinska Institutet, Stockholm

[2] Department of Medicine, Serafimerlasarettet, Stockholm

来源：

SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY | 1968年 / 3卷 / 04期

关键词：

Enzyme tests; Gastrointestinal system; Sulphokinases;

D O I：

10.3109/00365526809180131

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

A survey of the distribution of phenol and steroid sulphokinases in the mucosa of the gastrointestinal tract has been undertaken by the use of 35S-labelled 3'phosphoadenosine-5'phosphosulphate (PAPS). The specimens studied were obtained from stomach, jejunum, ileum, and colon. Phenol and oestrone sulphokinase were present in all levels of the gastrointestinal tract. The various steroid alcohol sulphokinases studied (dehydroepiandrosterone (DHA), androsterone, etiocholane-3αol-17-one, pregnane-3αol-20-one, and pregnane-3 βol-20-one) were detected in the jejunal mucosa only. The optimal pH of some sulphokinases were estimated and found to be 6.3 for DHA sulphokinase, 5.5 for androsterone sulphokinase, and 7.2 for phenol sulphokinase in a preparation of jejunal mucosa. © 1968 Informa UK Ltd.

引用

页码：369 / +

页数：1

共 28 条

[1] H-3-ANDROSTENE-3-BETA,17-BETA-DIOL-S35-SULFATE TO H-3-DEHYDROISOANDROSTERONE-S35-SULFATE INVIVO - AN EXAMPLE OF THE DIRECT METABOLISM OF A STEROID CONJUGATE [J].