GLOMERULAR SIALOPROTEIN

被引:154
作者
MOHOS, SC
SKOZA, L
机构
[1] Department of Pathology, New York Medical College, New York, NY 10029
关键词
D O I
10.1126/science.164.3887.1519
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The high content of sialic acid in the glomerulus is associated with the cell membrane of epithelial cells lining the basement membrane. Whereas enzyme studies indicate that sialic acid is a determinant of the nephritogenic antigen, the physicochemical properties of this nephritogenic glycoprotein suggest that sialic acid may have an important role in the filtration mechanism.
引用
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页码:1519 / &
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