CHARACTERISTICS OF IMMUNOGLOBULIN SYNTHESIZED EARLY IN THE DEVELOPMENT OF XENOPUS-LAEVIS

被引：5

作者：

LEVERONE, L

SUHAR, T

BROWN, RD

ARMENTROUT, RW

机构：

[1] Department of Biological Chemistry, University of Cincinnati College of Medicine, Cincinnati, OH 45267

来源：

DEVELOPMENTAL BIOLOGY | 1979年 / 68卷 / 01期

关键词：

D O I：

10.1016/0012-1606(79)90265-3

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A radioimmune assay has been used to detect the onset of immunoglobulin synthesis during development. In Xenopus laevis, immunoglobulin is first produced at stage 35 of embryonic development or about the time of emergence of the embryo from its jelly coat. At all embryonic stages measured, beginning at stage 35, both 19 and 7 S immunoglobulin are found. These immunoglobulins contain heavy and light chains identical in size to adult Xenopus IgM. These observations suggest the presence of both cell-associated and circulating IgM in Xenopus embryos. © 1979.

引用

页码：319 / 325

页数：7

共 13 条

[1] FILM DETECTION METHOD FOR TRITIUM-LABELED PROTEINS AND NUCLEIC-ACIDS IN POLYACRYLAMIDE GELS [J].

BONNER, WM ;

LASKEY, RA .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1974, 46 (01) :83-88

[2] DIRECT EVIDENCE FOR IMMUNOGLOBULINS ON SURFACE OF THYMUS LYMPHOCYTES OF AMPHIBIAN LARVAE [J].

DUPASQUIER, L ;

LOOR, F ;

WEISS, N .

EUROPEAN JOURNAL OF IMMUNOLOGY, 1972, 2 (04) :366-+

[3]

DUPASQUIER L, 1976, COLD SPRING HARB SYM, V41, P771

[4]

GURDON JB, 1974, CONTROL GENE EXPRESS

[5]

HADJIAZIMI I, 1971, IMMUNOLOGY, V21, P463

[6]

HADJIAZIMI I, 1976, IMMUNOLOGY, V30, P587

[7] HUMORAL ANTIBODIES TO SOLUBLE-ANTIGENS IN LARVAE OF XENOPUS-LAEVIS [J].

JURD, RD ;

LUTHERDAVIES, SM ;

STEVENSON, GT .

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY, 1975, 50 (NB1) :65-+

[8]

KESSLER SW, 1975, J IMMUNOL, V115, P1617

[9]

KIDDER GM, 1973, J EMBRYOL EXP MORPH, V29, P73

[10]

MARCHALONIS JJ, 1973, TRANSPLANT REV-DENMA, V14, P3

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