(O-HYDROXYPHENYL)METHYLPHOSPHONIC ACIDS - SYNTHESIS AND POTENTIOMETRIC DETERMINATIONS OF THEIR PKA VALUES

被引：28

作者：

BOHMER, V

VOGT, W

CHAFAA, S

MEULLEMEESTRE, J

SCHWING, MJ

VIERLING, F

机构：

[1] UNIV MAINZ,INST ORGAN CHEM,JJ BECHER WEG 18-20,W-6500 MAINZ,GERMANY

[2] UNIV STRASBOURG 1,EHICS,CHIM PHYS LAB,CNRS,URA 405,F-67000 STRASBOURG,FRANCE

来源：

HELVETICA CHIMICA ACTA | 1993年 / 76卷 / 01期

关键词：

D O I：

10.1002/hlca.19930760108

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(o-Hydroxyphenyl)methylphosphonic acids are readily obtained from o-(bromomethyl)- or o-(hydroxy-methyl)phenols and trialkyl phosphites. Subsequent hydrolysis leads to the corresponding phosphonic acids. For a series of such compounds, the pK(a) values have been determined by potentiometry. Their dependence on additional substituents in the aromatic ring is discussed in terms of electronic and steric effects.

引用

页码：139 / 149

页数：11

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