AN EXTREMELY MILD AND STEREOCONTROLLED CONSTRUCTION OF 1,2-TRANS-BETA-GLYCOSIDIC LINKAGES CAPITALIZING ON BENZYL-PROTECTED GLYCOPYRANOSYL DIETHYL PHOSPHITES AS GLYCOSYL DONORS

被引：66

作者：

HASHIMOTO, S ^{[1
]}

UMEO, K ^{[1
]}

SANO, A ^{[1
]}

WATANABE, N ^{[1
]}

NAKAJIMA, M ^{[1
]}

IKEGAMI, S ^{[1
]}

机构：

[1] TEIKYO UNIV,FAC PHARMACEUT SCI,SAGAMIKO,KANAGAWA 19901,JAPAN

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 13期

关键词：

D O I：

10.1016/0040-4039(95)00263-C

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly stereocontrolled 1,2-trans-beta-glycosidation reaction without neighboring group participation has been developed by using benzyl-protected glycopyranosyl diethyl phosphites as glycosyl donors and boron trifluoride etherate as a promoter. The present method exhibits the highest level of 1,2-trans-beta-selectivity known to date for glycosidations with a non-participating group on O-2.

引用

页码：2251 / 2254

页数：4

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