THE SYMPATHETIC NERVOUS-SYSTEM MODULATES ANTIBODY-RESPONSE TO THYMUS-INDEPENDENT ANTIGENS

被引：109

作者：

MILES, K

QUINTANS, J

CHELMICKASCHORR, E

ARNASON, BGW

机构：

[1] UNIV CHICAGO, PRITZKER SCH MED, DEPT NEUROL, CHICAGO, IL 60637 USA

[2] UNIV CHICAGO, DEPT PATHOL, CHICAGO, IL 60637 USA

[3] UNIV CHICAGO, DEPT NEUROL, CHICAGO, IL 60637 USA

[4] UNIV CHICAGO, LA RABIDA INST, DEPT PEDIAT, CHICAGO, IL 60637 USA

[5] UNIV CHICAGO, COMM IMMUNOL, CHICAGO, IL 60637 USA

来源：

JOURNAL OF NEUROIMMUNOLOGY | 1981年 / 1卷 / 01期

关键词：

D O I：

10.1016/0165-5728(81)90012-6

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Sympathetic nerve endings were destroyed with 6-hydroxydopamine (6-OHDA) and the response to thymus-dependent and -independent antigens compared in 6-OHDA-treated and control mice. A significantly enhanced plaque-forming cell response to 2 thymus-independent antigens was observed in the 6-OHDA-treated mice; in contrast, the response to a thymus-dependent antigen was normal. Selective modulation of antibody response by the sympathetic nervous system is indicated.

引用

页码：101 / 105

页数：5

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