POLYMER-INDUCED AND SALT-INDUCED TOROIDS OF HEXAGONAL DNA

被引：91

作者：

UBBINK, J ^{[1
]}

ODIJK, T ^{[1
]}

机构：

[1] DELFT UNIV TECHNOL,FAC CHEM ENGN & MAT SCI,DEPT POLYMER TECHNOL,2600 GA DELFT,NETHERLANDS

来源：

BIOPHYSICAL JOURNAL | 1995年 / 68卷 / 01期

关键词：

D O I：

10.1016/S0006-3495(95)80158-X

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

A model is proposed for polymer- and salt-induced toroidal condensates of DNA, based on a recent theory of the undulation enhancement of the electrostatic interaction in the bulk hexagonal phase of semiflexible polyions. In a continuum approximation, the thermodynamic potential of a monomolecular toroid may be split up in bulk, surface, and curvature contributions. With the help of an approximate analytical minimization procedure, the optimal torus dimensions are calculated as a function of the concentrations of inert polymer and added salt. The stability of the torus is analyzed in terms of its surface tension and a bulk melting criterion. The theory should be applicable to psi-toroids that are not too thick.

引用

页码：54 / 61

页数：8

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