INTRACELLULAR RECEPTORS AND SIGNAL TRANSDUCERS AND ACTIVATORS OF TRANSCRIPTION SUPERFAMILIES - NOVEL TARGETS FOR SMALL-MOLECULE DRUG DISCOVERY

被引：80

作者：

ROSEN, J

DAY, A

JONES, TK

JONES, ETT

NADZAN, AM

STEIN, RB

机构：

[1] Ligand Pharmaceuticals, Inc, San Diego, California 92121

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1995年 / 38卷 / 25期

关键词：

D O I：

10.1021/jm00025a001

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：4855 / 4874

页数：20

共 120 条

[1]

ALLAN GF, 1992, J BIOL CHEM, V267, P19513

[2] STEROID-HORMONE RECEPTORS AND INVITRO TRANSCRIPTION [J].

ALLAN, GF ;

TSAI, SY ;

OMALLEY, BW ;

TSAI, MJ .

BIOESSAYS, 1991, 13 (02) :73-78

[3] THE ORIGIN OF NUCLEAR RECEPTOR PROTEINS - A SINGLE PRECURSOR DISTINCT FROM OTHER TRANSCRIPTION FACTORS [J].

AMERO, SA ;

KRETSINGER, RH ;

MONCRIEF, ND ;

YAMAMOTO, KR ;

PEARSON, WR .

MOLECULAR ENDOCRINOLOGY, 1992, 6 (01) :3-7

[4] RETINOID ACTIVATION OF RETINOIC ACID RECEPTORS BUT NOT OF RETINOID-X RECEPTORS PROMOTES CELLULAR-DIFFERENTIATION AND REPLICATION OF HUMAN CYTOMEGALOVIRUS IN EMBRYONAL CELLS [J].

ANGULO, A ;

SUTO, C ;

BOEHM, MF ;

HEYMAN, RA ;

GHAZAL, P .

JOURNAL OF VIROLOGY, 1995, 69 (06) :3831-3837

[5] A RETINOIC ACID RECEPTOR-ALPHA ANTAGONIST SELECTIVELY COUNTERACTS RETINOIC ACID EFFECTS [J].

APFEL, C ;

BAUER, F ;

CRETTAZ, M ;

FORNI, L ;

KAMBER, M ;

KAUFMANN, F ;

LEMOTTE, P ;

PIRSON, W ;

KLAUS, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (15) :7129-7133

[6] CLONING OF HUMAN MINERALOCORTICOID RECEPTOR COMPLEMENTARY-DNA - STRUCTURAL AND FUNCTIONAL KINSHIP WITH THE GLUCOCORTICOID RECEPTOR [J].

ARRIZA, JL ;

WEINBERGER, C ;

CERELLI, G ;

GLASER, TM ;

HANDELIN, BL ;

HOUSMAN, DE ;

EVANS, RM .

SCIENCE, 1987, 237 (4812) :268-275

[7] GENE-REGULATION BY STEROID-HORMONES [J].

BEATO, M .

CELL, 1989, 56 (03) :335-344

[8] 3,5,3'-TRIIODOTHYRONINE RECEPTOR AUXILIARY PROTEIN (TRAP) ENHANCES RECEPTOR-BINDING BY INTERACTIONS WITHIN THE THYROID-HORMONE RESPONSE ELEMENT [J].

BEEBE, JS ;

DARLING, DS ;

CHIN, WW .

MOLECULAR ENDOCRINOLOGY, 1991, 5 (01) :85-93

[9] INTERACTION OF GLUCOCORTICOID ANALOGS WITH THE HUMAN GLUCOCORTICOID RECEPTOR [J].

BERGER, TS ;

PARANDOOSH, Z ;

PERRY, BW ;

STEIN, RB .

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, 1992, 41 (3-8) :733-738

[10] IDENTIFICATION OF SYNTHETIC RETINOIDS WITH SELECTIVITY FOR HUMAN NUCLEAR RETINOIC ACID RECEPTOR-GAMMA [J].

BERNARD, BA ;

BERNARDON, JM ;

DELESCLUSE, C ;

MARTIN, B ;

LENOIR, MC ;

MAIGNAN, J ;

CHARPENTIER, B ;

PILGRIM, WR ;

REICHERT, U ;

SHROOT, B .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1992, 186 (02) :977-983

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