HETEROGENEITY OF DNA-REPAIR - IMPLICATIONS FOR HUMAN-DISEASE AND ONCOLOGY

被引：11

作者：

BOHR, VA

EVANS, MK

机构：

[1] National Cancer Institute, Laboratory of Molecular Pharmacology, Division of Cancer Treatment, NIH, Bethesda, Maryland 20892

来源：

PEDIATRIC HEMATOLOGY AND ONCOLOGY | 1990年 / 7卷 / 01期

关键词：

Chromatin organization; DNA repair;

D O I：

10.3109/08880019009034319

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

DNA repair studies used to be confined to measurements representing an average over the entire mammalian genome. It is now possible to study repair processes at subgenomic levels including specific genes. We will describe such results and discuss the impact they may have on our understanding of important oncological processes. Also, we will describe and discuss some clinical conditions that may have some effect in DNA damage processing. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

引用

页码：47 / 69

页数：23

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